Welcome to the world of BIOTECH FARM LTD, where innovation meets expertise, and advanced research becomes reality. If you are active in the Israeli biomed and biotech industry and are looking to advance the development of your drugs and medical devices, you have come to the right place. We are here to offer you much more than a facility for large animal research; we are here to be your partners on the journey, from the initial idea to the critical stages before regulatory submission.
Meet BIOTECH FARM LTD: Vision, Expertise, and Dedication to the Future of Biomed
BIOTECH FARM LTD is not just another company in the field. We are a unique entity offering comprehensive services, based on a state-of-the-art facility, meticulously managed and providing close scientific support. What makes us the "last word" in the field? It is our holistic approach, which combines advanced technology, meticulous planning that meets the highest standards, and a team that lives and breathes research. Our facilities are equipped with the most advanced equipment, and ongoing management ensures maximum efficiency, preservation of data quality, and animal welfare. Our scientific support is not limited to words; it is expressed in professional advice, assistance in planning studies, and close guidance at every stage of your project.
Behind BIOTECH FARM LTD are the leading entrepreneurs, Adir Korach and Rinat Bornstein-Korach, who have accumulated over 25 years of rich experience in leading and managing complex studies. This experience is the greatest asset we bring to the table – a deep understanding of research challenges, familiarity with changing regulatory requirements, and practical knowledge that is irreplaceable. Our professional team, which includes expert veterinarians, experienced project managers, and skilled technicians, is purposeful and committed to the success of your projects. We see every client as a partner, and work in close collaboration with companies large and small, in Israel and abroad. All this, out of a deep belief that we contribute to the good of humanity and the welfare of animals alike, while adhering to ethical principles and high standards of care.
Research and Development Stages You Can Advance With Us: From Pre-Regulation to GLP Validation
At BIOTECH FARM LTD, we specialize in the most critical research and development stages for you: pre-regulatory trials in large animals and validation studies under GLP conditions. These stages are necessary milestones on the road to approval of medical products.
Pre-regulatory trials in large animals are the stage where you test the initial safety and efficacy of your drug or medical device in an animal model closest to humans. This stage is essential for collecting data that will allow you to make informed decisions about further development and prepare for regulatory requirements. We at BIOTECH FARM LTD will help you plan and conduct these studies in the best way, while adhering to precise protocols and collecting high-quality data.
GLP (Good Laboratory Practice) validation studies are studies conducted under a strict quality system, ensuring the reliability, consistency, and integrity of the data submitted to regulatory authorities. Compliance with GLP standards is a prerequisite for obtaining marketing authorization for drugs and medical devices in many countries. Our facilities, processes, and team at BIOTECH FARM LTD are prepared and ready to support these studies, and ensure that your project meets the most stringent requirements. We understand the importance of every detail and are committed to providing you with reliable data that will stand up to any scrutiny.
Accelerating Biotech Innovation: Comprehensive Support for Drug and Medical Device Development – Everything You Need in One Place
BIOTECH FARM LTD is located near the Rehovot Science Park, a strategic location that places us at the heart of the Israeli biotechnology ecosystem. This proximity allows you easy access, facilitates collaborations, and connects you to the center of activity and innovation. We see ourselves as a pivotal hub that feeds the development of biotechnological research and development.
We make it easier for you to manage the in vivo large animal trial phase in several key ways:
First, we provide you with a top-notch breeding ground and research facility. What does this mean in practice? Optimal housing conditions for animals, a fully controlled environment (temperature, humidity, lighting), advanced biological security systems, and all the equipment required to conduct complex studies. All of these contribute directly to the welfare of the animals and the quality of the data produced in your research.
Secondly, we foster a skilled and professional team in the fields of veterinary medicine, project management, and technical support. Our team does not just perform tasks; it is an active partner in thinking, offering creative solutions, flexible and adaptable to the changing needs of each project. They become an integral part of your team, providing proactive support at every stage.
Third, we advance the project together with you, in close collaboration with your scientists, mechanical teams, software vendors, quality assurance managers, and your management's requirements. We understand that a successful project requires synergy between all parties involved, and we know how to create these connections and ensure full coordination. For example, we can integrate your development engineers into the implantation process of a new device, or work with your software experts to integrate unique monitoring systems.
Our Clientele and Diverse Projects: Rich Experience That Serves Your Goals
Our clientele is diverse and includes industrial companies, academic institutions, and research bodies. This diversity demonstrates our ability to adapt to different needs, understand diverse research methodologies, and deal with changing regulatory challenges. The experience we have gained working with a wide range of clients serves you directly, and allows us to offer you customized solutions.
In the field of drug development, we support projects that include:
- Drug development: From the early discovery stages to advanced pre-clinical studies, we help you assess the potential of new molecules.
- Drug delivery: We understand the challenges involved in developing effective and safe delivery systems, and provide the models and expertise needed to test them in large animals. Whether you are developing nanoparticles, liposomes, or other sustained release systems, we can assist you.
- Testing of active ingredients and metabolites: We conduct comprehensive studies to test the concentrations of active ingredient and metabolites in different tissues, the clearance of the substance from the body (pharmacokinetics – PK) and its effect on the body (pharmacodynamics – PD), as well as short- and long-term safety assessment. These studies are essential for understanding the profile of your drug.
In the field of medical devices, our customers come from a wide range of fields, such as:
- Surgical instruments: Development and testing of innovative surgical devices, implants, and technologies for minimally invasive surgery.
- New technological approaches: We support developments that incorporate advanced technologies such as artificial intelligence, medical robotics, and advanced diagnostic systems.
- New solutions for a wide range of diseases: We are proud to be part of developing solutions that improve the quality of life of patients and change the face of medicine.
Surgical Procedures at the Highest Level: Advanced Operating Room for Your Development Service
The surgical procedures performed at BIOTECH FARM LTD are an exact replica of what is done in a sophisticated operating room in a hospital. We understand the critical importance of a sterile environment, advanced equipment, and a skilled team to perform complex surgeries. Our operating rooms are equipped with advanced anesthesia machines, comprehensive physiological monitoring systems, optimal surgical lighting, and all the tools required to perform a wide range of procedures. This environment not only ensures the welfare and safety of the animals, but also creates trust and ensures high data quality, which is essential for the success of your project.
Many of our clients are pleased with the unique opportunity to allow the inventing surgeon to perform the unique surgery himself. This is the real time to draw conclusions, improve the device or technique, and directly observe the performance of your development. We see this as a significant advantage that accelerates the development cycle and allows for immediate feedback. In these cases, our support team will enable the surgery to be performed smoothly, carefully monitor the anesthesia, and document vital parameters and images to complete the knowledge base collected for the project. The documentation can include continuous physiological data, video recordings, simulations, and more, and it is managed and transmitted to you in an orderly and secure manner. This comprehensive approach contributes significantly to the success of the project and the preparation of a strong and convincing regulatory submission file.
Ethical and Scientific Commitment: Reducing the Use of Animals Through Advanced Ex-Vivo Models
At BIOTECH FARM LTD, we strongly believe in the need to reduce the number of animals required for research, and actively work to promote this principle. This commitment is not just a statement; it is an integral part of our philosophy and the way we advise our clients. We advocate the 3Rs principles (Replacement, Reduction, Refinement) and strive to integrate them into every aspect of our operation.
We believe that a correct development path will allow you, our customers, to learn as much as possible about ex vivo models before moving to in vivo experiments. Ex vivo models, which use tissues or organs outside the living body, allow you to perform initial scans, test feasibility, investigate mechanisms of action, and more, all at a lower cost and in a more ethical manner. The goal is to arrive at the necessary in vivo experiment when your chances of success with the first prototype are much higher. This approach not only saves you valuable time and resources, but also significantly reduces the use of animals.
To this end, BIOTECH FARM LTD allows you to receive available ex vivo samples. These samples can be:
- Stored in various solutions: Such as saline or PBS, depending on your research needs.
- Prepared with or without adjacent connective tissue: For maximum adaptation to the type of tests you will perform.
- Preserved in a variety of ways: In formalin, refrigerated, or deep-frozen, depending on the analytical techniques you will use.
- Supplied anywhere: We take care of complex logistics and maintain the integrity of the sample until it reaches you.
- Collected sterilely: For collecting stem cells or primary cells for further culture. We adhere to strict sterility conditions to ensure the quality and viability of the samples.
This service directly supports your research and development needs in the early stages, in validating biological targets, or in developing new testing methods. We at BIOTECH FARM LTD are committed to providing you with the tools and support needed to advance your research in the most efficient, ethical, and scientific way. Contact us today to discuss how we can help you realize your scientific vision.
click here for more info: https://biotechfarm.co.il/